![]() A careful evaluation of this very small region is of critical importance for proper nodal staging in nasopharyngeal cancer patients. Several (five) normal lymph nodes with small size (<0.5 cm in short-axis diameter) and without abnormal morphology were observed in bilateral axillae, more of them on the left side. Conclusion: SLNI with the possibility of metastasis was more frequently observed in nasopharyngeal carcinoma, advancing the nodal status without significantly influencing the T and M stages. There were no abnormal lymph nodes in the right supraclavicular area or other lymph node levels of the neck. Multivariate regression analysis revealed an increased cervical (p < 0.01) and thoracic (p = 0.001) lymph node involvement in patients with SLNI. Age, gender, tumor size, and systemic metastases were not identified as statistically significant variables contributing to SLNI. In all HNT studied, no apparent metastatic predilection tendency for the supraclavicular region was observed, as opposed to the well-described Virchow's node. Results: Nasopharyngeal carcinoma demonstrated significant SLNI (p < 0.01) however, other subtypes of HNT did not. Patients and Methods: 270 patients diagnosed with HNT were enrolled in the study (194 males and 96 females, mean age 54.9 ± 14.7 years (range 18-89 years)). We also investigated the impact of different variables on SLNI. Lymphadenopathy is not a disease but a symptom of a disease or medical condition. Background: In this study, we aimed to determine the correlation between supraclavicular lymph node involvement (SLNI) and metastatic potential, frequency, and metastases predilection sites in patients diagnosed with various head and neck tumors (HNT) and staged via positron emission tomography/computed tomography (PET/CT) imaging. Swollen lymph nodes, also known as lymphadenopathy, are a symptom that typically occurs when your body is fighting an infection. ![]()
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